Storyline
PerturbPlan: An analytical framework for designing Perturb-seq experiments
CRISPR screens with single-cell RNA-seq readouts provide a powerful tool for characterizing the functions of noncoding elements and genes. However, designing these experiments to balance statistical power and cost is challenging, given the large number of design parameters.
Published 2026-05-23 04:46 UTCUpdated 2026-05-23 14:41 UTC
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Evidence trail (top sources)
top sources (1 domains)domains are deduped. counts indicate coverage, not truth.1 top source shown
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Overview
CRISPR screens with single-cell RNA-seq readouts provide a powerful tool for characterizing the functions of noncoding elements and genes. However, designing these experiments to balance statistical power and cost is challenging, given the large number of design parameters.
Score total
0.75
Momentum 24h
2
Posts
2
Origins
1
Source types
1
Duplicate ratio
0%
Continuity snapshot
- Trend status: flat.
- Continuity stage: seed.
- Current status: open.
- 2 current source-linked posts are attached to this storyline.
All evidence
All evidence
CMAPS: Causal Mediation Analysis of Perturbation Screens with Application to Genome-scale Perturb-seq Data
bioRxiv (all subjects) · biorxiv.org · 2026-05-23 14:41 UTC
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- biorxiv.org (1)