Storylines

Gilead acquires Tubulis to enhance oncology ADC pipeline with $5 billion deal

Gilead Sciences has agreed to acquire Tubulis for $3.15 billion upfront plus up to $1.85 billion in milestone payments.

Avalyn Pharma files IPO to fund phase 3 trials of inhaled lung disease drugs

Coverage discusses speculative scenarios; treat as market chatter and see linked sources.

New insights into cancer treatment response and resistance from spatial and transcriptomic analyses

Coverage discusses speculative scenarios; treat as market chatter and see linked sources.

New computational frameworks advance spatial transcriptomics analysis in cancer research

Recent studies introduce innovative computational methods to enhance spatial transcriptomics analysis, enabling deeper insights into cell-cell communication, regulatory programs, and tumor microenvironment heterogeneity.

CHMP PROM minutes for the meeting on 12 May 2025

Internship goals?

Hi all, Hoping for some advice from people already working in biopharma R&D in the UK. I am halfway through a PhD in therapeutic antibody development (at a good UK university). When I graduate I am hoping to get a job with one of the big biopharma companies working on biologics R&D. I have lots of experience in academic labs, but no industry experience so am planning to do a 3 month internship in

Revolution pancreatic cancer drug nearly doubles survival in key trial

The subject of buyout rumors this year, Revolution posted Phase 3 results one analyst called a “game changer” in a tough-to-treat tumor.

Deep-Plant: a supervised foundation model for plant regulatory genomics

Large-scale sequence-to-function deep learning models have demonstrated unparalleled ability to model biological sequences and have revolutionized the field of regulatory genomics. However, the majority of such efforts have centered on human and mammalian systems, leaving plant regulatory genomics comparatively underexplored. To address this gap, we introduce Deep-Plant, a supervised foundation mo

Prion Protein Deficiency Results in Synaptic, Neural Network and Behavioral Alterations

The cellular form of the prion protein (PrPC) is known for its involvement in the pathogenesis of prion diseases. Recent research implicates the physiological isoform of PrP in neuronal development, excitability, and synaptic plasticity, as well as in other biological processes. However, its precise function in the development and function of neurons remains poorly understood. Here, we investigate

Jeito closes 'record' $1.2bn Europe-focused biopharma fund

Jeito closes 'record' $1.2bn Europe-focused biopharma fund Phil.Taylor Wed, 08/04/2026 - 11:16

A Context-Aware Single-Cell Proteomics Analysis pipeline.

Single-cell proteomics (SCP) by mass spectrometry can now quantify hundreds to thousands of proteins per cell, but the field still lacks standardised analytical pipelines that accommodate the diversity of instruments, sample preparation workflows and biological contexts encountered in practice. Existing workflows, largely adapted from single-cell transcriptomics, do not account for the informative

Sanofi's bispecific lunsekimig has mixed readouts in phase 2

Sanofi's bispecific lunsekimig has mixed readouts in phase 2 Phil.Taylor Tue, 07/04/2026 - 10:42

Spyre drug for inflammatory bowel disease shows promise in early study

The therapy, which works similarly to Takeda’s blockbuster Entyvio, showed remission rates that suggest a “best-in-class” profile, the company said.

FDA hands another rejection to Replimune's melanoma therapy

FDA hands another rejection to Replimune's melanoma therapy Phil.Taylor Mon, 13/04/2026 - 08:20

IDEAYA/Servier PKC drug aces uveal melanoma trial

IDEAYA/Servier PKC drug aces uveal melanoma trial Phil.Taylor Mon, 13/04/2026 - 13:19