Signal

Distinct molecular signatures differentiate pediatric and adult dilated cardiomyopathy and predict pediatric outcomes

Recent studies reveal that pediatric dilated cardiomyopathy (DCM) exhibits fundamentally different transcriptional programs compared to adult DCM, with only 7.4% overlap in differentially expressed genes.

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  • Age-dependent transcriptional programs in pediatric vs adult DCM
    medRxiv
  • Circulating miRNA-protein signatures predict pediatric DCM outcomes
    bioRxiv