Signal
New computational models enhance single-cell and bulk sequencing analysis for cancer and gene regulation research
Recent advances in computational methods improve the accuracy of detecting somatic nucleotide variants and copy number variations in single-cell sequencing by integrating bulk sequencing data.
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- bioRxiv preprints on single-cell and bulk sequencing methodsbiorxiv.org
- Integrative modeling of read depth and B-allele frequency improves single-cell copy number calling from targeted DNA...bioRxiv (all subjects)
- Comparing bulk and single-cell methodologies and models to profile gene expression, chromatin accessibility and regul...bioRxiv (all subjects)